Table 5.

Sleep disorders, cardiovascular disease and stroke in epidemiological studies.

STUDY	DESIGN	N	OUTCOME	OR/HR (95% CI)
OSA
SHHS	Cross-sectional	6,424	Heart failure	2.4 (1.2–4.6)
Shahar et al., 2001			CAD	1.3 (1.0–1.6)
			Stroke	1.6 (1.0–2.5)
WSC	Cross-sectional	1,475	Stroke	3.8 (1.2–12.5)
Arzt et al., 2005
Yaggi et al., 2005	Prospective cohort	1,022	Stroke or death	2.0 (1.1–3.5)
Munoz et al., 2006	Prospective cohort	394	Stroke	2.5 (1.0–6.0)
SHHS	Prospective cohort	5,422	Stroke	Men, 2.9 (1.1–7.4)
Redline et al., 2010				Women, 1.2 (0.7–2.2)

OR, odds ratio; HR, hazards ratio; OSA, obstructive sleep apnea; SHHS, Sleep Heart Health Study; PSG, polysomnography; HTN, hypertension; CVD, cardiovascular disease; CAD, coronary artery disease; WSC, Wisconsin Sleep Cohort; ARIC, Atherosclerosis Risk In Communities