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. Author manuscript; available in PMC: 2019 Apr 17.
Published in final edited form as: Chem Rev. 2018 Sep 7;119(2):1323–1455. doi: 10.1021/acs.chemrev.8b00201

Figure 2.

Figure 2

Stucture of hCAII (PDB 1CA2). The protein backbone is shown in a ribbon style, with coordinating residues and the hydrogen-bonding Thr199 shown in sticks and colored by element (carbons in gray). The Zn2+ ion is shown as an orange sphere and the coordinated water molecule is shown as a red sphere. Metal-ligand coordination bonds are shown as dashed yellow lines and hydrogen bonds as dashed magenta lines. The stylistic features of this figure are used throughout this review. All protein images were generated using PyMOL (The PyMOL Molecular Graphics System, Version 2.0 Schrödinger, LLC).