Skip to main content
. Author manuscript; available in PMC: 2019 Apr 17.
Published in final edited form as: Chem Rev. 2018 Sep 7;119(2):1323–1455. doi: 10.1021/acs.chemrev.8b00201

Figure 85.

Figure 85

Mechanism of resistance to vancomycin. Left: Schematic of vancomycin binding to D-Ala-D-Ala. The hydrogen bond eliminated in resistant bacteria is colored red. Right: Schematic of vancomycin binding to D-Ala-D-Lactate. The site of the mutation is highlighted in cyan.