Table 6.
N-glycan traits in normal and CKD
| Normal | CKD | ||||||
|---|---|---|---|---|---|---|---|
| N-glycan | Structure | Median(IQR) | Range | Median(IQR) | Range | W | p |
| GP1 | FA2 | 6.36(2.79) | (5.02–7.81) | 6.61(2.90) | (5.39–8.29) | 18,846 | 0.260 |
| GP2 | FA2B | 2.37(0.85) | (2.02–2.87) | 2.47(0.72) | (2.08–2.81) | 19,007 | 0.425 |
| GP3 | A2[6]BG1 | 0.08(0.05) | (0.07–0.12) | 0.09(0.03) | (0.07–0.11) | 8801 | 0.992 |
| GP4 | FA2[6]G1 | 4.39(1.20) | (3.98–5.19) | 4.77(1.70) | (3.68–5.39) | 8731 | 0.878 |
| GP5 | FA2[3]G1 | 1.83(0.64) | (1.57–2.21) | 1.84(0.66) | (1.48–2.15) | 8411 | 0.419 |
| GP6 | FA2[6]BG1 | 1.18(0.31) | (1.04–1.36) | 1.31(0.57) | (1.00–1.58) | 18,446 | 0.052 |
| GP7 | M6D1-D2 | 0.99(0.18) | (0.92–1.09) | 0.95(0.23) | (0.83–1.07) | 7897 | 0.063 |
| GP8 | A2G2 | 1.12(0.31) | (0.99–1.30) | 1.10(0.37) | (0.97–1.34) | 8650 | 0.750 |
| GP9 | A2BG2 | 0.09(0.04) | (0.09–0.12) | 0.09(0.03) | (0.09–0.12) | 8603 | 0.678 |
| GP10 | FA2G2 | 3.70(1.50) | (3.14–4.64) | 3.46(1.39) | (2.89–4.28) | 7688 | 0.022* |
| GP11 | FA2BG2 | 0.73(0.21) | (0.62–0.83) | 0.71(0.19) | (0.62–0.81) | 8677 | 0.792 |
| GP12 | A2[3]BG1S[3]1 | 1.00(0.16) | (0.93–1.09) | 0.97(0.18) | (0.89–1.06) | 8077 | 0.136 |
| GP13 | FA2[3]G1S[3]1 | 0.81(0.19) | (0.72–0.91) | 0.81(0.32) | (0.66–0.99) | 19,213 | 0.707 |
| GP14 | A2G2S[6]1 | 10.75(1.48) | (9.97–11.46) | 11.19(1.64) | (10.46–12.11) | 18,049 | 0.006* |
| GP15 | A2BG2S[6]1 | 0.38(0.11) | (0.34–0.45) | 0.38(0.10) | (0.34–0.44) | 8690 | 0.813 |
| GP16 | FA2G2S[6]1 | 5.82(1.35) | (5.16–6.52) | 5.28(1.17) | (4.67–5.84) | 7158 | 0.001* |
| GP17 | FA2BG2S[3]1 | 1.56(0.56) | (1.33–1.90) | 1.58(0.48) | (1.32–1.81) | 8780 | 0.958 |
| GP18 | A2G2S[3,6]2 | 3.40(0.76) | (3.01–3.77) | 3.35(0.63) | (3.11–3.74) | 19,338 | 0.904 |
| GP19 | M9 | 1.12(0.22) | (1.00–1.22) | 1.08(0.22) | (0.97–1.20) | 8136 | 0.171 |
| GP20 | A2G2S[3,6]2 | 25.47(3.68) | (23.55–27.23) | 25.65(4.67) | (23.38–28.06) | 19,094 | 0.536 |
| GP21 | A2BG2S[3,6]2 | 0.51(0.17) | (0.44–0.61) | 0.51(0.17) | (0.44–0.61) | 8780 | 0.958 |
| GP22 | FA2G2S[3,6]2 | 4.38(0.96) | (4.01–4.97) | 4.12(1.17) | (3.76–4.93) | 7531 | 0.009* |
| GP23 | FA2BG2S[3,6]2 | 1.89(0.68) | (1.61–2.29) | 1.99(0.66) | (1.66–2.32) | 19,036 | 0.460 |
| GP24 | A3G3S[3,6]2 | 1.73(0.62) | (1.41–2.03) | 1.84(0.73) | (1.38–2.11) | 19,217 | 0.713 |
| GP25 | A3BG3S[3,6]2 | 0.15(0.06) | (0.12–0.19) | 0.16(0.06) | (0.14–0.19) | 18,544 | 0.081 |
| GP26 | A3G3S[3,3]2 | 1.63(0.48) | (1.38–1.87) | 1.68(0.59) | (1.36–1.95) | 19,095 | 0.537 |
| GP27 | A3G3S[3,3,3]3 | 0.48(0.34) | (0.30–0.64) | 0.50(0.37) | (0.34–0.72) | 18,936 | 0.346 |
| GP28 | A3G3S[3,3,6]3 | 0.80(0.32) | (0.64–0.96) | 0.82(0.29) | (0.63–0.92) | 8612 | 0.692 |
| GP29 | FA3G3S[3,3,3]3 | 0.19(0.06) | (0.16–0.22) | 0.18(0.05) | (0.16–0.21) | 8498 | 0.529 |
| GP30 | A3G3S[3,3,6]3 | 5.89(2.01) | (4.86–6.87) | 5.94(2.19) | (4.64–6.84) | 8598 | 0.671 |
| GP31 | FA3G3S[3,3,6]3 | 0.52(0.29) | (0.42–0.72) | 0.50(0.21) | (0.42–0.63) | 8218 | 0.229 |
| GP32 | A3F1G3S[3,3,3]3 | 1.46(0.57) | (1.24–1.82) | 1.56(0.55) | (1.25–1.80) | 19,136 | 0.594 |
| GP33 | A4G4S[3,3,3]3 | 1.83(1.44) | (1.17–2.61) | 2.03(1.51) | (1.34–2.85) | 18,932 | 0.342 |
| GP34 | A4G4S[3,3,6]3 | 0.40(0.15) | (0.33–0.48) | 0.41(0.10) | (0.34–0.45) | 8706 | 0.838 |
| GP35 | A4F1G3S[3,3,3]3 | 0.26(0.15) | (0.19–0.35) | 0.29(0.16) | (0.21–0.36) | 18,959 | 0.371 |
| GP36 | A4G4S[3,3,3,3]4 | 0.44(0.11) | (0.40–0.51) | 0.45(0.13) | (0.39–0.53) | 19,149 | 0.612 |
| GP37 | A4G4S[3,3,3,3]4 | 0.49(0.21) | (0.39–0.60) | 0.48(0.19) | (0.38–0.58) | 8512 | 0.548 |
| GP38 | A4G4S[3,3,3,6]4 | 0.90(0.27) | (0.78–1.06) | 0.91(0.24) | (0.77–1.01) | 8632 | 0.722 |
| GP39 | A4F1G4S[3,3,3,6]4 | 0.51(0.25) | (0.41–0.67) | 0.55(0.23) | (0.45–0.67) | 18,916 | 0.325 |
Data presented as median interquartile range (IQR). W-Wilcoxon statistic, Tests of significance were two tailed (*p < 0.05) and are bold