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. 2018 Nov 21;7(23):e009975. doi: 10.1161/JAHA.118.009975

Table 1.

Study Characteristics

First Author Year Country Study Type Population Sample Size EAT Method EAT Value
Bakkum8 2015 the Netherlands Cross‐sectional Suspected CAD 208 PET‐CT 113.8±48.1 cm3
Cavalcante9 2012 United States Cross‐sectional Self‐referred screening 110 MDCT Men, 101±51 cm3
Women, 67±40 cm3
Al Chekakie7 2010 United States Case‐control AF and controls 273 MDCT Sinus rhythm, 76.1±36.3 mL;
AF, 101.6±44.1 mL
Doesch11 2012 Germany Case‐control Established CAD 158 Cases
and 40 controls 		MRI Control, 31±8 g/m2; CAD, 29±10 g/m2;
CAD and EF <50%, 26±8 g/m2;
CAD and EF >50%, 36±11 g/m2
Doesch12 2013 Germany Case‐control DCM 112 Cases
and 48 controls 		MRI Control, 62.1±14.4 g; DCM, 47.2±15.2 g;
control, 66±15.3 mL; DCM, 50.2±16.2 mL;
control, 31.7±5.6 g/m2; DCM, 24±7.5 g/m2;
control, 33.5±6.4 mL/m2; DCM, 25.5±8 mL/m2
Doesch10 2010 Germany Case‐control CHF (LVEF <35%)
(ICM=36; DCM=30) 		66 Cases
and 31 controls 		MRI Control, 71±13 mL; CHF, 46±11 mL;
control, 36±5 mL/m2; CHF, 24±5 mL/m2;
control, 67±13 g; CHF, 43±11 g;
control, 34±4 g/m2; CHF, 22±5 g/m2
Ede13 2014 Turkey Cross‐sectional Suspected CAD 106 MDCT 38±31 cm3
Faustino14, a 2011 Portugal Cross‐sectional Not specified 78 MDCT Threshold of 44.1 mL defined by ROC curve (72% sensitivity and 50% specificity) for diastolic dysfunction
Fernando15, a 2015 United States Cross‐sectional AF before ablation 20 MRI 125.7±56.7 mL
Fontes‐Carvalho16 2014 Portugal Cross‐sectional Postmyocardial infarction 225 MDCT 113.6±43.2 cm3
Fox17 2009 United States Cross‐sectional Substudy of Framingham 997 MDCT Women, 108±41 cm3; men, 136.5±54.4 cm3
Hachiya18 2014 Japan Cross‐sectional Suspected CAD 134 MDCT 77.1±29.6 cm3/m2
Khawaja19 2011 Unites States Cross‐sectional Suspected CAD 381 MDCT Normal LVEF, 114.5±98.5 cm3;
LVEF <55%, 83.5±67.1 cm3
Konishi20 2012 Japan Cross‐sectional Suspected CAD 229 MDCT Diastolic dysfunction, 184±61 cm3;
normal function, 154±58 cm3
Lai21 2015 Taiwan Cross‐sectional Self‐referred screening 318 MDCT 80.6±33 mL
Liu22 2011 United States Cross‐sectional Blacks 1402 MDCT Men, 79.8±37.1 mL;
women, 67.1±29.0 mL
Longenecker23, a 2016 Cross‐sectional Patients with HIV 46 HIV+ and 23 HIV− MDCT HIV+ with DD, median of 120 (74–143) mL;
HIV+ with normal function, median of 72 (54–100) mL;
HIV−, not specified
Ng24 2016 Australia Cross‐sectional Suspected CAD 130 MDCT Total, 97.5±43.7 cm3;
men, 103.7±39.5 cm3;
women, 90.9±47.4 cm3
Ruberg3 2010 United States Cross‐sectional Obese with metabolic syndrome 28 Cases
and 18 controls 		MRI Controls, 85±66 mL; subjects, 161±88 mL;
controls, 1.1±0.7 mL/g; subjects, 2.0±1.1 mL/g
Vanni25, a 2015 Italy Case‐control Not specified 19 NAFLD
and 9 controls 		MRI NAFLD, 228.1±112.9 mL;
controls, 66.8±25.2 mL
Vural26 2014 Turkey Case‐control Suspected CAD 63 CACS 137±56 cm3
Wu27 2015 Taiwan Cross‐sectional Compensated CHF 50 Cases
and 20 controls 		MRI Control, 45.8 (39.4–50.3) mL; CHF+VT/VF, 51.5 (46.6–59.8) mL); CHF and no VT/VF, 44.0 (33.9–48.3) mL
Yamashita28, a 2012 Japan Cross‐sectional Suspected CAD 286 MDCT EAT, 71.6±37.9 (10.5–179.9) mL

Values are mean±SD or mean (range). AF indicates atrial fibrillation; CACS, coronary artery calcium score; CAD, coronary artery disease; CHF, congestive heart failure; DCM, dilated cardiomyopathy; DD, diastolic dysfunction; EAT, epicardial adipose tissue; ICM, ischemic cardiomyopathy; LVEF, left ventricular ejection fraction; MDCT, multidetector computed tomography; MRI, magnetic resonance imaging; NAFLD, nonalcoholic fatty liver disease; PET‐CT, positron emission tomography–computed tomography; ROC, receiver operating characteristic; VT/VF, ventricular tachycardia/ventricular fibrillation.

a

This is a conference abstract.