Table 4.

Arrhythmia Recurrence and Repeated Ablation by Utah Stage of LA Fibrosis

Recurrence of Atrial Arrhythmia or Repeated Ablation	Utah Stages of LA Fibrosis				P Value for Trend
	I	II	III	IV
No. of events	42	54	34	27
Incidence rate, per 10 000 person‐years	5.7	8.0	9.2	25.9
Hazard ratio (95% CI)
Model 1a	1.00	1.34 (0.89–2.03)	1.39 (0.87–2.22)	3.17 (1.88–5.33)	<0.001
Model 2b	1.00	1.40 (0.92–2.12)	1.45 (0.90–2.33)	2.89 (1.69–4.94)	<0.001
Model 3c	1.00	1.45 (0.96–2.20)	1.47 (0.90–2.38)	3.04 (1.76–5.26)	<0.001
Model 4d	1.00	1.55 (1.00–2.40)	1.36 (0.83–2.25)	2.73 (1.57–4.75)	0.001

CI indicates confidence interval; LA, left atrial.

^aAdjusted for age, sex, body mass index, smoking status, and atrial fibrillation type.

^bIncludes variables in model 1 and additional adjustment for heart failure, hypertension, diabetes mellitus, and stroke history.

^cIncludes variables in model 2 and additional adjustment for class I and III antiarrhythmic use, calcium channel blocker use, angiotensin‐converting enzyme inhibitor or angiotensin II receptor blocker use, and β‐blocker use.

^dIncludes variables in model 3 and additional adjustment for left ventricular ejection fraction, LA volume, LA area, left ventricular diameter, estimated glomerular filtration rate, and mitral valve regurgitation.