Table 1.
Baseline Characteristics of Patients Undergoing TAVI
| Total (n=704) | Responders (n=376) | Nonresponders (n=328) | P Value | |
|---|---|---|---|---|
| Age, y | 81.6 (77.6–86.0) | 81.3 (77.5–85.7) | 81.8 (78.0–86.3) | 0.204 |
| Female | 386 (54.8) | 200 (53.2) | 186 (56.7) | 0.350 |
| BMI, kg/m2 | 26.2 (23.6–29.4) | 26.2 (23.7–29.0) | 26.5 (23.5–30.0) | 0.236 |
| Atrial fibrillation | 302 (42.9) | 148 (39.4) | 154 (47.0) | 0.042 |
| CAD | 510 (72.4) | 271 (72.1) | 239 (72.9) | 0.815 |
| COPD | 115 (16.3) | 56 (14.9) | 59 (18.0) | 0.268 |
| Diabetes mellitus | 230 (32.7) | 120 (31.9) | 110 (33.5) | 0.647 |
| Dyslipidemia | 358 (50.9) | 188 (50.0) | 170 (51.8) | 0.628 |
| Hypertension | 638 (90.6) | 329 (87.5) | 309 (94.2) | 0.002 |
| PAD | 135 (19.2) | 55 (14.6) | 80 (24.4) | 0.001 |
| CVD | 133 (18.9) | 62 (16.5) | 71 (21.6) | 0.081 |
| PAH | 132 (18.8) | 85 (22.6) | 47 (14.3) | 0.005 |
| LVEF | ||||
| <35% | 67 (9.5) | 41 (10.9) | 26 (7.9) | 0.179 |
| 35–45% | 101 (14.3) | 65 (17.3) | 36 (11.0) | 0.017 |
| 45–55% | 131 (18.6) | 72 (19.1) | 59 (18.0) | 0.693 |
| >55% | 405 (57.5) | 198 (52.7) | 207 (63.1) | 0.005 |
| GFR | ||||
| <30 mL/min | 76 (10.8) | 36 (9.6) | 40 (12.2) | 0.264 |
| 30–45 mL/min | 157 (22.3) | 79 (21.0) | 78 (23.8) | 0.378 |
| 45–60 mL/min | 281 (39.9) | 145 (38.6) | 136 (41.5) | 0.433 |
| >60 mL/min | 190 (27.0) | 116 (30.9) | 74 (22.6) | 0.013 |
| History of smoking | 157 (22.3) | 78 (20.7) | 79 (24.1) | 0.288 |
| Log. EuroSCORE (%) | 18.8 (11.9–28.4) | 18.6 (11.6–28.4) | 19.0 (12.7–28.5) | 0.721 |
| NT‐proBNP, pg/mL | 1991 (746–4235) | 2822 (1113–5575) | 1187 (507–2782) | <0.001 |
| AVA, cm2 | 0.7 (0.6–0.9) | 0.7 (0.5–0.8) | 0.8 (0.6–0.9) | <0.001 |
| MPG, mm Hg | 37 (28–49) | 41 (30–53) | 35 (25–43) | <0.001 |
| Diastolic dysfunction ≥ II | 442 (62.8) | 234 (62.2) | 208 (63.4) | 0.746 |
| RV dysfunction | 110 (15.6) | 61 (16.2) | 49 (14.9) | 0.640 |
| MR III–IV | 36 (5.1) | 20 (5.3) | 16 (4.9) | 0.791 |
| TR III–IV | 47 (6.7) | 23 (6.1) | 24 (7.3) | 0.525 |
Values are presented as count (percentage) or median (interquartile range). AVA indicates aortic valve area; BMI, body mass index; CAD, coronary artery disease; COPD, chronic obstructive pulmonary disease; CVD, cerebrovascular disease; GFR, glomerular filtration rate; LVEF, left ventricular ejection fraction; MPG, mean pressure gradient; MR, mitral regurgitation; NT‐proBNP, N‐terminal pro–B‐type natriuretic peptide; PAD, peripheral artery disease; PAH, pulmonary arterial hypertension; RV, right ventricle; TAVI, transcatheter aortic valve implantation; TR, tricuspid regurgitation.