Table 1.
Baseline, Operative, and Postoperative Characteristics
| Clinical Characteristic | Full Cohort (n=120) | Preoperative Sample Available (n=82) | No Preoperative Sample (n=38) | P Value | 3 Time Points Available (n=57) | No 24‐h Sample (n=63) | P Value |
|---|---|---|---|---|---|---|---|
| Female sex, n (%) | 52 (43.3) | 37 (45.1) | 15 (39.5) | 0.56 | 27 (47.4) | 25 (39.7) | 0.40 |
| Age at surgery, median (range), d | 14.5 (1.0–120) | 20 (1–120) | 8.5 (2–118) | 0.21 | 11 (1–120) | 17 (2–119) | 0.95 |
| Preterm, n (%) | 16 (13.3) | 13 (15.9) | 3 (7.9) | 0.39 | 9 (15.8) | 7 (11.1) | 0.45 |
| Weight, kg, median (range) | 3.5 (2.1–7.9) | 3.6 (2.1–7.9) | 3.5 (2.1–5.4) | 0.73 | 3.5 (2.1–7.9) | 3.6 (2.1–7.4) | 0.66 |
| Aristotle score,28 comprehensive, median (range) | 10.0 (3.0–19.5) | 10.0 (3.0–19.5) | 9.0 (3.0–14.5) | 0.63 | 10.3 (3.0–19.5) | 9.0 (3.0–14.5) | 0.14 |
| CPB time, median (range), min | 137.5 (0–399) | 137.5 (54–399) | 137 (0–277) | 0.29 | 142 (56–399) | 130 (0–277) | 0.17 |
| Cross‐clamp time, median (range), min | 74.5 (0–241) | 75 (0–241) | 69.5 (0–205) | 0.83 | 79 (0–241) | 69 (0–205) | 0.19 |
| Deep hypothermic circulatory arrest, median (range), min | 0 (0–154) | 0 (0–154) | 0 (0–77) | 0.54 | 0 (0–154) | 0 (0–77) | 0.99 |
| Selective cerebral perfusion, median (range), min | 0 (0–115) | 0 (0–115) | 0 (0–78) | 0.99 | 0 (0–115) | 0 (0–82) | 1.00 |
| Single‐ventricle physiological feature, n (%) | 38 (31.9) | 25 (30.9) | 13 (34.2) | 0.72 | 20 (35.1) | 18 (29.03) | 0.48 |
| Mortality, n (%) | 9 (7.6) | 7 (8.5) | 2 (5.4) | 0.72 | 6 (10.5) | 3 (4.8) | 0.31 |
| Combined primary outcome, n (%)a | 11 (9.3) | 8 (9.9) | 3 (8.1) | 1.00 | 6 (10.5) | 5 (8.2) | 0.66 |
| CICU length of stay, median (range), d | 6 (1–42) | 6 (1–42) | 5.0 (2.8–29) | 0.93 | 6 (1–42) | 6 (1–40) | 0.49 |
| Vasoactive inotropic score29, 30 at 24 h, median (range) | 7 (0–30) | 7.3 (0–30) | 7 (0–26) | 1.00 | 8 (0–30) | 5.5 (0–26) | 0.80 |
| Duration of mechanical ventilation, median (range), h | 44.5 (0.1–762.6) | 45.2 (0.1–762.6) | 44.2 (0.5–453.1) | 0.90 | 43.1 (0.1–762.6) | 45.6 (0.5–453.1) | 0.80 |
CICU indicates cardiac intensive care unit; CPB, cardiopulmonary bypass.
a
Death in hospital or within 30 days, cardiac arrest, or need for extracorporeal membrane oxygenation.