Table 3.

Incrementally Adjusted Risk for All‐Cause Mortality

	HR (95% CI)	P Value
Model 1	2.72 (2.11–3.56)	<0.001
Model 2	2.67 (2.06–3.64)	<0.001
Model 3	2.22 (1.68–2.97)	0.014
Model 4	1.74 (1.08–2.93)	0.041

Model 1: unadjusted all‐cause mortality risk based on the extent of QRS fragmentation (QRS‐f). Model 2: includes all variables in model 1 plus adjustment for the following ECG parameters: QRS duration, JT interval, and rhythm (sinus, paced rhythm, atrial fibrillation, and atrial flutter/tachycardia). Model 3: includes all variables in model 2 plus adjustment for patient demographic characteristics (current age, sex, age at the time of tetralogy of Fallot [TOF] repair and type of TOF repair [transannular patch vs nontransannular patch]). Model 4: includes all variables in model 3 plus adjustment for history of sustained ventricular tachycardia and/or defibrillator implantation, moderate right ventricular dysfunction by qualitative assessment, and left ventricular ejection fraction <40%. Hazard ratio (HR) is expressed per incremental risk per class/extent of QRS‐f (none, mild, moderate, severe).