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. 2019 Feb 15;8(4):e010745. doi: 10.1161/JAHA.118.010745

Figure 2.

Figure 2

Eliminating E‐prostanoid 4 receptor from all tissues leads to reduced acute vasodilator responses to prostaglandin E2 (PGE 2). Acute blood pressure (BP) changes to PGE 2 and angiotensin II administration were measured through the carotid artery. A, The PGE 2‐induced acute BP decrease was significantly reduced in total‐body knockout (TBKO) mice. B, Short‐term administration of angiotensin II caused similar acute BP increases in both genotypes. n=4 and n=5 per group. Data are expressed as median with range. *P<0.05.