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E‐prostanoid 4 receptor in vascular smooth muscle cells regulates acute vascular responses to prostaglandin E2 (PGE 2) and angiotensin II. A, The decrease in blood pressure (BP) after short‐term administration of PGE 2 was significantly attenuated in smooth muscle knockout (SMKO) mice. B, Acute pressor responses to angiotensin II were significantly enhanced in SMKO mice. n=8 to 9 per group. Data are expressed as mean±SEM. *P<0.05.
