Figure 8.

Absence of E‐prostanoid 4 receptor from vascular smooth muscle cells has no effect on angiotensin II–dependent hypertension. A, There were no differences in daily mean arterial pressure (MAP) between smooth muscle knockout (SMKO) mice and control during angiotensin II infusion. B, Net change in MAP during the 21 days of angiotensin II infusion compared with baseline (change in blood pressure [∆BP]) was similar in control and SMKO mice. n=10 per group. Data are expressed as mean±SEM. N.S. indicates not significant.