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. 2019 Feb 13;8(4):e011704. doi: 10.1161/JAHA.118.011704

Figure 3.

Figure 3

Basal blood pressure was significantly elevated in endothelial cell–specific inositol 1,4,5‐trisphosphate receptor triple knockout (ECTKO) mice. Blood pressures were measured in unstrained mice using an implantable telemetry system. A, Systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean blood pressure (MBP) in control and ECTKO mice. The data were presented at times indicated on a 24‐hour scale, and data shown at each point represent 1‐hour rolling averages of data sampled each minute in 3 consecutive days. n=7 mice per group. B, Mean values for SBP, DBP, and MBP were calculated during the day (8 am–8 pm) and night (8 pm–8 am). n=7 mice per group. Significance was determined using a 2‐tailed, unpaired, Student t test or 2‐way ANOVA analysis with Bonferroni post hoc test. Error bars represent mean±SEM. ***P<0.001 vs control.