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Endothelial cell senescence (A) and intracellular sirtuin 1 (B) and miR‐34a (C) expression in response to treatment with microparticles from antiretroviral therapy–treated HIV‐1–seropositive men and healthy men. D, Relation between cellular miR‐34a and sirtuin 1 expression in microparticle‐treated human umbilical vein endothelial cells. Values are mean±SEM. AU indicates arbitrary unit. *P<0.05.
