Table 1.
Hormonal and Metabolic Features of Study Subjects
| Variable | Healthy Subjects | CAD Group | P Value |
|---|---|---|---|
| Sex ratio (women/men) | 90:41 | 72:59 | |
| Age, y | 55.46±11.40 | 55.27±11.78 | 0.202 |
| Glucose, mmol/L | 5.22±0.66 | 6.52±2.14 | <0.0001 |
| HbA1C, % | 5.50±0.35 | 16.68±7.51 | <0.0001 |
| TCH, mmol/L | 4.92±0.98 | 4.06±1.12 | <0.0001 |
| Triglyceride, mmol/L | 1.36±0.81 | 1.80±1.72 | 0.07 |
| LDL‐C, mmol/L | 2.93±0.85 | 2.23±1.01 | <0.0001 |
| HDL‐C, mmol/L | 1.41±0.46 | 1.07±0.27 | <0.0001 |
| C‐reactive protein, mg/L | 0.77±0.91 | 3.13±4.50 | <0.01 |
| AST, U/L | 22±7.95 | 26.68±21.80 | 0.187 |
| BNP, μg/L* | 31.2±21.2 (5/131) | 147.5±184.64 (22/131) | 0.135 |
| CK, U/L* | 112.33±38.26 (5/131) | 123.68±97.11 | 0.77 |
| Whole blood MYO, ng/mL* | 25.9±10.7 (2/131) | 50.22±50.06 (19/131) | 0.59 |
| Whole blood troponin I, μg/L* | 0.3 (1/42) | 0.45±0.45 (12/131) | |
| CKMB, μg/L | † | 15.17±14.65 (16/131) | |
| LDH, U/L | 160.66±17.17 | 194.0±58.30 | 0.33 |
| MMB, ng/mL* | 0.95±0.28 (6/131) | 1.71±1.22 | 0.13 |
| TNI, ng/mL* | 0.01 (2/131) | 2.90±6.07 (24/131) | |
| β1‐AA (OD values)‡ | 0.32 (0.12–0.49) | 0.86 (0.56–1.28) | <0.001 |
Data are given as mean±SD unless otherwise indicated. β1‐AA indicates autoantibodies against the second extracellular loop of β1‐adrenergic receptor; AST, aspartate aminotransferase; BNP, brain natriuretic peptide; CAD, coronary heart disease; CK, creatine kinase; CKMB, CK isoenzyme MB; HbA1C, glycated hemoglobin; HDL‐C, high‐density lipoprotein cholesterol; LDH, lactate dehydrogenase; LDL‐C, low‐density lipoprotein cholesterol; OD, optical density; TCH, total cholesterol; TNI, troponin I; MYO, myoglobin; MMB,CK‐MB mass.*Data in parenthesis are number/total.†The healthy control group did not test the CKMB index.‡Data are given as median (interquartile range).