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Glycocalyx measurements. A, The noninvasive camera records live video of RBCs moving through sublingual vessels. B, Schematic illustration of glycocalyx structure. C, The healthy glycocalyx is relatively impermeable to RBCs, resulting in a small PBR. D, Glycocalyx damage allows RBCs to penetrate further into the glycocalyx, increasing PBR width. PBR indicates perfused boundary region; RBC, red blood cell.
