Table 2.
Composite Variables for Glycocalyx Assessment
| Variable | Normotensive (n=73) | GDM (n=21) | Late‐Onset PE (n=29) | Early Onset PE (n=14) |
|---|---|---|---|---|
| Suggested composite variables for pregnant women | ||||
| PBR 10–16 | 2.520 (2.469–2.572)* | 2.495 (2.399–2.591)* | 2.555 (2.473–2.636)* | 2.721 (2.604–2.838) |
| RBC 10–16 | 0.598 (0.587–0.610)* | 0.609 (0.587–0.631)* | 0.604 (0.585–0.622)* | 0.564 (0.537–0.591) |
| Composite variables calculated by the GlycoCheck software | ||||
| PBR 5–25 | 2.441 (2.392–2.490)* | 2.448 (2.356–2.539)* | 2.461 (2.384–2.539)* | 2.612 (2.500–2.723) |
| RBC 5–25 | 0.548 (0.537–0.558)* | 0.549 (0.529–0.568) | 0.549 (0.533–0.566)* | 0.518 (0.495–0.542) |
| PBR 5–9 | 1.243 (1.225–1.261) | 1.263 (1.230–1.296) | 1.261 (1.233–1.290) | 1.283 (1.242–1.323) |
| PBR 10–19 | 2.706 (2.651–2.762)* | 2.690 (2.587–2.793)* | 2.746 (2.658–2.834) | 2.872 (2.746–2.998) |
| PBR 20–25 | 3.092 (2.992–3.192)* | 3.101 (2.915–3.287)* | 3.086 (2.928–3.244)* | 3.426 (3.199–3.653) |
Data are presented as mean (95% CI). All variables were adjusted for caffeine intake. RBC composites denote composite values for the percentage of vessel segments that are filled with RBCs. Each composite variable was calculated as the median value of the averages of each vessel‐size category within the specified range (ie, 5–9 includes vessels with a median RBC column width of 5, 6, 7, 8, and 9 μm). Data were analyzed by univariate ANOVA (fixed factor: group; covariate: caffeine intake; post hoc test: least significant differences). GDM indicates gestational diabetes mellitus; PBR, perfused boundary region; PE, preeclampsia; RBC, red blood cell.
*
P<0.05 in comparison to early PE.