FIGURE 5.

Cortisol treatment increases the single neuron prediction error. (A) Bar graphs of single neuron mouse location prediction errors for all neurons (457 ± 25 cells per group) averaged over all recording sessions (8.58 ± 0.16 sessions) [mean ± SEM]. Calculations were averaged by mice (n = 6) per group for left and right running directions separately. Cortisol-treated mice had a significantly higher prediction error (p < 0.05) compared to untreated mice for the rightward running direction only, but a higher prediction error for both running directions when compared to citalopram-treated mice. Asterisks show group comparisons with ^∗p < 0.05 and ^∗∗∗p < 0.005. (B) Mouse location prediction errors using Bayesian decoders trained on ensemble neural data. No significant group effects were found for the ensemble decoders. Data shown as mean ± SEM, (n = 6 mice).