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. 2019 Mar 1;10:140. doi: 10.3389/fphar.2019.00140

Table 1.

GO enrichment analysis results of differentially up-regulated genes and down-regulated genes (DEGs).

Term P value FDR
Up-regulated genes (DEGs) RNA processing 3.23E-06 0.00478286
Non-membrane-bounded organelle 4.53E-13 5.56E-10
Intracellular non-membrane-bounded organelle 4.53E-13 5.56E-10
Ribonucleoprotein complex 5.00E-11 6.15E-08
Intracellular organelle lumen 1.81E-09 2.22E-06
Organelle lumen 3.09E-09 3.80E-06
Membrane-enclosed lumen 4.90E-09 6.02E-06
Nuclear lumen 1.32E-06 0.00162684
Nucleolus 1.59E-06 0.00194848
RNA binding 5.78E-16 6.77E-13
mRNA binding 2.37E-05 0.02904478
Down-regulated genes (DEGs) RNA processing 1.41E-10 2.21E-07
Posttranscriptional regulation of gene expression 2.29E-09 3.58E-06
mRNA metabolic process 1.81E-08 2.82E-05
mRNA processing 2.40E-07 3.74E-04
Regulation of translation 1.05E-06 0.00164623
Chromatoid body 2.05E-06 0.00250038
P granule 3.57E-06 0.00436073
Germ plasm 3.57E-06 0.00436073
Pole plasm 3.57E-06 0.00436073
Intracellular non-membrane-bounded organelle 1.94E-05 0.02370618
Non-membrane-bounded organelle 1.94E-05 0.02370618
RNA binding 1.46E-23 1.83E-20