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. 2019 Jan 8;8(1):e010157. doi: 10.1161/JAHA.118.010157

Figure 4.

Figure 4

The effect of down‐regulation of miR‐15a/15b on apoptosis of mesenchymal stem cells under oxygen and glucose deprivation (OGD) condition. A and B, The expression levels of miR‐15a and miR‐15b from Control, OGD 12 hours, OGD 12 hours+miR‐15a/15b inhibitors, and OGD 12 hours+miR‐15a/15b mimics were detected by quantitative reverse transcription–polymerase chain reaction. Data are expressed as median (quartile 1–quartile 3), n=3. **P<0.01 vs Control; ## P<0.01 vs OGD 12 hour group; & P<0.05, && P<0.01 vs OGD 12 hour group. C‐F, The expression levels of vascular endothelial growth factor receptor 2 (VEGFR2) (C and D) and Bcl‐2 (E and F) from Control, OGD 12 hours, OGD 12 hours+miR‐15a/15b inhibitors, and OGD 12 hours+miR‐15a/15b mimics were detected by Western blotting assay. Data are expressed as median (quartile 1–quartile 3), n=3. **P<0.01 vs Control; ## P<0.01 vs OGD 12 hour group.