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. 2019 Mar 7;9:3856. doi: 10.1038/s41598-019-40402-2

Table 1.

Demographics and manifestations of the 253 HFMD cases included in the study.

CVA6 EV71 CA16 other enterovirus non-enterovirus
Cases (%) 133 (52.6) 11 (4.3) 13 (5.1) 7 (2.8) 89 (35.2)
Male/female ratio 1.9 (87/46) 1.8 (7/4) 1.6 (8/5) 1.3 (4/3) 1.6 (55/34)
Age (year), mean ± SD 1.47 ± 1.16a 2.91 ± 1.30 1.54 ± 1.17 2.42 ± 1.63 1.59 ± 1.10
Fever ( ≥ 39 °C) (%) 28.6 (38/133) 0.0 (0/11) 0.0 (0/13) 14.3 (1/7) 20.2 (18/89)
Intraoral rash (%) 48.9 (65/133) 36.4 (4/11) 53.8 (7/13) 71.4 (5/7) 47.2 (42/89)
Rash on limbs (%) 99.2 (132b/133) 100.0 (11/11) 100.0 (13/13) 100.0 (7/7) 100.0 (89/89)
Rash on trunk (%) 27.8 (37/133) 9.1 (1/11) 0.0 (0/13) 0.0 (0/7) 25.8 (23/89)
Rash on buttocks (%) 71.4 (95/133) 72.7 (8/11) 92.3 (12/13) 57.1 (4/7) 57.3 (51/89)
Rash on head and face (%) 9.8 (13/133) 0.0 (0/11) 0.0 (0/13) 14.3 (1/7) 6.7 (6/89)
Vesicles (%) 97.8 (130/133) 100.0 (11/11) 100.0 (13/13) 100.0 (7/7) 94.4 (84/89)
Skin itchiness (%) 7.5 (10/133) 0.0 (0/11) 0.0 (0/13) 0.0 (0/7) 3.4 (3/89)

aTwo older HFMD cases (14-year-old and 23-year-old) were excluded.

bOne case had an intraoral rash and rash on trunk and buttocks.