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. 2019 Mar 7;9:3793. doi: 10.1038/s41598-019-40507-8

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Mitochondrial biogenesis and ATP levels in the obe^td15 retina. Quantitative RT-PCR was used to determine relative mRNA expression levels of polg2 (a), fis1 (b), and opa1 (c) at 6 and 12 months post fertilization (mpf) (n = 3 for each age, mean ± SEM). (f) ATP levels were examined using a luciferin-luciferase assay in the obe^td15 retina at 6 and 12 mpf (n = 5 for each age, mean ± SEM). *p < 0.05, ***p < 0.001.