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. 2019 Mar 7;9:3808. doi: 10.1038/s41598-019-40527-4

Table 1.

Characteristics of articles included in the meta-analysis.

Author Year Cancer Material Cut-off value Region Endpoint Patient CD103+ (%)
Djenidi22 2015 Non-small cell lung cancer WS none (continuous) all three OS, DFS 98
Wang16 2016 Breast cancer TMA 90th percentile epithelium OS 424 43 (10.1)
Wang33 2015 Urothelial cell carcinoma WS >9cells/HPF epithelium OS 262 148 (56.5)
Bosmuller34 2016 HGSC TMA >1 cell/HPF epithelium OS 202 140 (69.3)
Santoiemma26 2016 Ovarian cancer TMA ≥10 cells/core epithelium OS 135 31 (23.0)
Koh23 2017 Squamous cell lung cancer TMA mean epithelium/stroma OS, DFS 378 108/111 (28.6/29.4)a
Workel20 2016 Endometrial adenocarcinoma TMA >27.28 cells/mm2 total DFS, DSS 253 84 (33.2)
Komdeur35 2017 Cervical cancer TMA >29 cells/mm2 total DFS, DSS 387 200 (51.7)
Zhou27 2018 Renal cell carcinoma WS >1 cell/HPF total DSS 200 117 (58.5)
Webb36 2013 Ovarian cancer TMA ≥5(1) cells/coreb TMA DSS 485 339 (69.9)

*OS: overall survival, DFS: disese-free survival, DSS: disease-specific survival, WS: whole slide, TMA: tissue microarray, HPF: high power field, HGSC: high grade serous ovarian cancer.

aPositive for epithelial area/positive for stromal area.

b≥5 cells/core to evaluate prognosis, ≥1 cell/core to evaluate positivity.