Table 4.
Overview of the Model 2.
| Abstract species (Model 2) | Detailed species (Model 1) | Remark |
|---|---|---|
| KinA | KinA | Kinetochore attached |
| KinU | KinU | Kinetochore unattached |
| Activator | Cdc20 | Activator |
| Promotor | APC/C | (inactive) Promotor that can be activated. |
| Promotor_A | APC/C:Cdc20 | Active Promotor, checkpoint deactivated, “go” signal |
| Inhibitor | O-Mad2, C-Mad2, C-Mad2:Cdc20, BubR1:Bub3, MCC | Inhibitor for the Promotor |
| Promotor_I | APC/C:MCC, APC/C:BCC, APC/C.C-Mad2:Cdc20 | Inactive Promotor, inhibited such that it cannot be activated directly. “Wait” signal. |