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. 2019 Feb 1;9(2):270–284.

Figure 3.

Figure 3

DANCR promotes migration and invasin, and induces EMT. A. DANCR inhibition decreased the migration and invasion of A549 cells as determined by transwell assays. B. DANCR overexpression increased the migration and invasion of H1299 cells as determined by transwell assays. C. qRT-PCR showed a significant increase in the expression of the epithelial markers, E-cadherin and α-catenin, and a corresponding reduction of the mesenchymal markers, N-cadherin, and Fibronectin in DANCR-depleted A549 cells, relative to control. D. qRT-PCR showed a significant decrease in the expression of the epithelial markers, E-cadherin and α-catenin, and a corresponding increase of the mesenchymal markers, N-cadherin, and Fibronectin in DANCR-overexpressed H1299 cells, relative to control. E. The protein expression of mesenchymal and epithelial markers in indicated stable cells was detected by western blot. Date are presented as the means ± SD. *P<0.05.