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Down-regulation of SFRP4 impairs the recruitment of T cells. A. The presentative image of FOXP3 staining by IHC. The asterisks marked the FOXP3+ Treg cells. B. The patients with high SFRP4 expression demonstrated a greater proportion of high infiltration of FOXP3+ Treg cells. C. The presentative image of SFRP4 and FOXP3 staining by IHC in the tumor tissue from KPC mice.
