Table 2.

Echocardiographic parameters of left ventricle (LV) and heart rate (HR) in Hannover Sprague-Dawley (HanSD) and Ren-2 transgenic rats (TGR) subjected to sham operation (non-MI) and myocardial infarction (MI) and treated with epoxyeicosatrienoic acid analog (EET-A) or soluble epoxide hydrolase inhibitor (c-AUCB), given alone or combined for 5 weeks since 24 h after MI.

	AWTd (mm)	LVDd (mm)	PWTd (mm)	AWTs (mm)	LVDs (mm)	PWTs (mm)	RWT (%)	HR (bpm)
HanSD
Sham (non-MI)	2.21 ± 0.09	8.82 ± 0.20	2.28 ± 0.09	3.44 ± 0.11	5.27 ± 0.16	3.39 ± 0.10	51.1 ± 2.1	360 ± 14
MI	1.69 ± 0.08†	11.70 ± 0.17†	2.41 ± 0.10	1.66 ± 0.07†	10.37 ± 0.21†	2.88 ± 0.13†	35.1 ± 0.9†	327 ± 11
MI + EET-A	1.61 ± 0.05	11.24 ± 0.17	2.26 ± 0.07	1.62 ± 0.06	9.65 ± 0.17	2.92 ± 0.09	34.6 ± 0.7	347 ± 8
MI + c-AUCB	1.61 ± 0.05	11.13 ± 0.16	2.34 ± 0.10	1.62 ± 0.05	9.62 ± 0.20	2.95 ± 0.11	35.6 ± 1.2	355 ± 7
MI + EET-A + c-AUCB	1.60 ± 0.07	11.13 ± 0.24	2.16 ± 0.05	1.70 ± 0.12	9.50 ± 0.29*	2.83 ± 0.07	34.0 ± 1.1	356 ± 7
TGR
Sham (non-MI)	2.64 ± 0.10	8.52 ± 0.17	2.57 ± 0.10	3.66 ± 0.14	5.44 ± 0.13	3.42 ± 0.10	65.1 ± 2.8	373 ± 13
MI	1.95 ± 0.08†	11.65 ± 0.29†	2.41 ± 0.09	2.03 ± 0.15†	10.35 ± 0.33†	3.16 ± 0.11	35.0 ± 1.6†	353 ± 11
MI + EET-A	1.88 ± 0.08	11.19 ± 0.30	2.41 ± 0.05	1.93 ± 0.13	9.90 ± 0.35	3.17 ± 0.06	38.1 ± 2.2	351 ± 15
MI + c-AUCB	1.84 ± 0.06	11.54 ± 0.17	2.40 ± 0.09	1.96 ± 0.14	10.28 ± 0.24	3.00 ± 0.09	35.3 ± 1.0	343 ± 10
MI + EET-A + c-AUCB	1.85 ± 0.08	11.47 ± 0.16	2.43 ± 0.11	1.94 ± 0.18	10.30 ± 0.16	3.10 ± 0.14	35.4 ± 1.7	321 ± 16

AWTd, diastolic anterior wall thickness; LVDd, diastolic LV diameter; PWTd, diastolic posterior wall thickness; AWTs, systolic anterior wall thickness; LVDs, systolic LV diameter; PWTs, systolic posterior wall thickness; RWT, relative wall thickness; bpm, beats per minute. Values are means ± SEM; ^†P < 0.05 MI vs. corresponding Sham (non-MI) group; ^∗P < 0.05 vs. corresponding MI group.