Figure 5.

Tonsil-derived mesenchymal stem cells (T-MSCs) were co-cultured with peripheral blood mononuclear cells under T helper 1 (Th1) or T helper 2 (Th2)-inducing conditions. (A) In the presence of T-MSCs, Th1 cells showed >50% decrease in interferon-gamma (IFN-γ) production and (B) Th2 showed >300% increase in interleukin-4 (IL-4) production compared with controls without T-MSCs. Values indicate the change in cytokine secretion (mean ± standard deviation) in the absence or presence of T-MSCs in three independent experiments. Error bars represent standard deviation.