Table 3.
Comparison between patients with good and poor outcomes
| Variable |
Early outcome (hospital discharge) |
Late outcome (1 yr after admission) |
||||
| Good outcome (n = 24; 57%) | Poor outcome (n = 18; 43%) | P value | Good outcome (n = 35; 84%) | Poor outcome (n = 7; 16%) | P value | |
| Age (years), median (IQR) | 11 (5-12.5) | 1.6 (1-8) | 0.026 | 10 (2-13) | 1.7 (0.9-3) | 0.014 |
| Male sex, n (%) | 14 (78) | 15 (62) | 0.289 | 24 (68) | 5 (71) | 0.881 |
| Evolution (days from initial symptoms), median (IQR) | 2.5 (2-10) | 7 (4-12) | 0.036 | 4 (2-10) | 7 (7-15) | 0.043 |
| Cardiac syndrome, n (%) | ||||||
| FM | 2 (8) | 10 (55) | < 0.001 | 7 (20) | 5 (71) | < 0.001 |
| CHF | 6 (25) | 4 (22) | 0.834 | 8 (23) | 2 (28) | 0.746 |
| Dysrhythmia | 3 (12) | 3 (16) | 0.793 | 6 (17) | 0 (0) | 0.237 |
| ACS-like | 13 (54) | 1 (5) | 0.001 | 14 (40) | 0 (0) | 0.041 |
| Viral prodromal, n (%) | 15 (62) | 14 (68) | 0.289 | 23 (65) | 6 (85) | 0.296 |
| Altered ECG, n (%) | 22 (91) | 17 (94) | 0.729 | 32 (91) | 7 (100) | 0.421 |
| CPR (mg/dL), median (IQR) | 4 (2-147) | 4 (3-125) | 0.443 | 4 (2-144) | 33 (3-156) | 0.415 |
| Troponin T (ng/mL), median (IQR) | 118 (5-580) | 91 (32-196) | 0.789 | 103 (5-610) | 52 (32-177) | 0.447 |
| NT-proBNP (pg/mL), median (IQR) | 291 (92-300) | 2700 (1955-4320) | < 0.001 | 300 (123-1955) | 5700 (2500-10321) | 0.002 |
| LVEF (%), median (IQR) | 65 (58-66) | 34 (28-41) | < 0.001 | 59 (41-66) | 29 (27-31) | < 0.001 |
| LVDD Z score > 2, n (%) | 9 (37) | 17 (94) | < 0.001 | 19 (54) | 7 (100) | 0.023 |
| Dyskinesia, n (%) | 11 (46) | 5 (27) | 0.233 | 15 (43) | 1 (14) | 0.155 |
| LGE in cMRI (n =21), n (%) | 12 (75) | 3 (60) | 0.517 | 14 (70) | 1 (100) | 0.517 |
| Positive Microbiology, n (%) | 12 (50) | 8 (44) | 0.307 | 16 (45) | 4 (57) | 0.666 |
IQR: Interquartile range; CHF: Congestive heart failure; SCD: Sudden cardiac death; ACS: Acute coronary syndrome; FM: Fulminant myocarditis; CRP: C-reactive protein; LVEF: Left ventricle ejection fraction; LVDD: Left ventricle diastolic dysfunction; LGE: Late gadolinium enhancement; cMRI: Cardiac magnetic resonance imaging.