Figure 1.

The selected transcripts of LMNA gene—transcript variant 1 (coding for lamin A protein) and transcript variants 2 and 6 (coding for lamin C), and transcript variant 7 arisen from mutated LMNA gene (coding for progerin). Farnesylated sequence and proteolytic site are indicated for lamin A transcript, as well as possible mutations in protein-coding sequence. Indicated miR-9-binding sites are present both in mRNA variant 1 and 7. siRNA binding site in present only in mRNA variant 7. Figure created based on NCBI database.