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. 2019 Feb 5;11(2):183. doi: 10.3390/cancers11020183

Figure 5.

Figure 5

Targeting melanoma Ag to CD169 on human MoDCs results in melanoma Ag presentation to T cells. IFNγ production by gp100280–288-specific HLA-A2.1 restricted T cell line after 24 h co-culture with MoDCs previously pulsed for 3 h with Ab:gp100 c onjugates specific for CD169, DC-SIGN or isotype control Ab (n = 5 healthy donors, each different symbol represents one donor). Statistical analysis matched one-way ANOVA with Sidak’s multiple comparison correction * p < 0.05, ** p < 0.01.