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Primary sequence alignment of Cx37 isoforms denoting deletions (-), point mutations (•), and the associated growth phenotypes (colored rectangles beneath mutant titles; black: cell death, red: growth arrest, green: proliferation) of each isoform when expressed in iRin cells. The mid-tail (M) region spans from P273 to R317. The terminal 16 amino acids (318–333) constitute the end-tail (E) region. For additional data pertaining to Cx37-WT, -273tr, and -S7D7 mutants, see [22,24,25].
