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. 2019 Feb 5;8(2):189. doi: 10.3390/jcm8020189

Table 1.

Summary of findings.

Outcomes № of Participants (Studies) Follow Up Certainty of the Evidence (GRADE) Relative Effect (95% CI) Anticipated Absolute Effects * (95% CI)
Risk with No Interventions to Promote Utilization of CR Risk Difference WITH Interventions to Promote Utilization of CR
Enrolment 3096 (19 RCTs) – 11 weeks ⊕⊕⊝⊝LOW 1,2 RR 1.27 (1.13 to 1.42) Study population
406 per 1000 110 more per 1000 (53 more to 171 more)
Adherence 1654 (9 RCTs) – 18 weeks ⊕⊕⊝⊝LOW 1,2 - SMD 0.38 SD higher (0.20 higher to 0.55 higher)
Completion 1565 (8 RCTs) – 24 weeks ⊕⊕⊕⊝MODERATE 2 RR 1.13 (1.02 to 1.25) Study population
649 per 1000 84 more per 1000 (13 more to 162 more)

* The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI—confidence interval; RCT—randomized controlled trial; RR—risk ratio; SD—standard deviation; SMD—standardized mean difference; CR—cardiac rehabilitation. GRADE Working Group grades of evidence. High certainty (4 ⊕): we are very confident that the true effect lies close to that of the estimate of the effect. Moderate certainty (3 ⊕): we are moderately confident in the effect estimate: the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different. Low certainty: (1 ⊕) our confidence in the effect estimate is limited: the true effect may be substantially different from the estimate of the effect. Very low certainty (0 ⊕): we have very little confidence in the effect estimate: the true effect is likely to be substantially different from the estimate of effect. 1 Heterogeneity suggests evidence of inconsistency, therefore quality of evidence downgraded by one level. 2 The included studies consisted of primarily white male participants, therefore quality of evidence downgraded by one level for indirectness.