Table 2.

DBMSC (CMDBMSC, SFDBMSC, and ICDBMSC) effects on macrophage expression of different functional markers, costimulatory molecules, co-inhibitory molecules, antigen presenting molecule, inflammatory cytokines, and anti-inflammatory markers as compared to untreated macrophages by flow cytometry recorded by mean of fluorescent intensity (MFI). Increased (↑, p < 0.05), decreased (↓, p < 0.05)), and no change (p > 0.05).

Markers	Types	CMDBMSC	SFDBMSC	ICDBMSC		Markers	Types	CMDBMSC	SFDBMSC	ICDBMSC
CD14	Functional Markers	↑	↑	No Change		IDO	Anti-inflammatory Markers	No Change	No Change	↓
CD163		↑	↑	↓		TGFβ1		No Change	No Change	No Change
CD204		No Change	No Change	↓		TGFβ1, 2, 3		No Change	No Change	No Change
CD206		No Change	↑	↓		HMOX-1		No Change	No Change	No Change
CD36		No Change	No Change	↓
B7H4		No Change	No Change	No Change
CD80	Costimulatory Molecules	No Change	No Change	No Change
CD86		↓	↓	↓
CD273	Co-Inhibitory Molecules	No Change	No Change	↓
CD274		No Change	No Change	↓
HLA-DR	Antigen Presenting Molecule	No Change	No Change	No Change
IL-1β	Inflammatory Cytokines	↓	↓	↑
IL-6		No Change	No Change	↓
IL-8		No Change	No Change	No Change
IL-12		No Change	↓	↓
IFN-γ		No Change	↑	↑
TNF-α		No Change	No Change	↑