Table 1.
Dual-specificity phosphatase (DUSP) mRNA expression measured by NGS analysis. Under the condition of fragments per kilobase of transcript per million (FPKM) >5 and fold change >2. IS increased the expression of DUSP1, DUSP5, DUSP5, and DUSP16 in astrocytes.
| Gene ID | Associated Gene Name | EntrezGene ID | Locus | FPKM (NHA-IS-10μM) |
FPKM (NHA) |
Ratio Ratio (NHA-IS-10μM/NHA) |
|---|---|---|---|---|---|---|
| ENSG00000079393 | DUSP13 | 51207 | 10:75094431-75182123 | 0.219633 | 0.0001 | 2196.33 |
| ENSG00000111266 | DUSP16 | 80824 | 12:12474209-12562383 | 52.219 | 14.1532 | 3.689554 |
| ENSG00000120129 | DUSP1 | 1843 | 5:172758225-172777774 | 221.988 | 38.2398 | 5.805156 |
| ENSG00000130829 | DUSP9 | 1852 | X:153642491-153651326 | 0.169448 | 0.070583 | 2.400708 |
| ENSG00000133878 | DUSP26 | 78986 | 8:33591331-33600106 | 3.46896 | 0.421005 | 8.239712 |
| ENSG00000138166 | DUSP5 | 1847 | 10:110497837-110511544 | 127.022 | 9.39548 | 13.51948 |
| ENSG00000143507 | DUSP10 | 11221 | 1:221701423-221742176 | 25.8229 | 1.7915 | 14.41412 |
| ENSG00000149599 | DUSP15 | 128853 | 20:31847636-31952092 | 27.5482 | 4.7307 | 5.823282 |
| ENSG00000158050 | DUSP2 | 1844 | 2:96143165-96145440 | 38.0541 | 2.74733 | 13.8513 |
| ENSG00000162999 | DUSP19 | 142679 | 2:183078558-183108519 | 0.118331 | 0.633702 | 0.18673 |
| ENSG00000167065 | DUSP18 | 150290 | 22:30635651-30669016 | 3.83218 | 9.21196 | 0.416001 |
| ENSG00000184545 | DUSP8 | 1850 | 11:1554043-1599184 | 36.2799 | 6.57598 | 5.517033 |
| ENSG00000189037 | DUSP21 | 63904 | X:44844003-44844888 | 0.147912 | 0.0001 | 1479.12 |