Table 2.
Primary tumor and tumor vascular thrombosis (TVT) response according to dose-fractionation regimens and pre- and post-treatment (Tx).
| Response | Dose-Fractionation Regimen, n (%) | p Value * | Pre-Tx to PBT Site, n (%) | p Value * | Post-Tx to PBT Site, n (%) | p Value * | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Regimen A | Regimen B | Regimen C | No | Yes | No | Yes | |||||
| Primary tumor | CR | 16 (40.0) | 51 (85.0) | 132 (92.3) | <0.001 | 47 (90.4) | 152 (79.6) | 0.405 | 174 (89.2) | 25 (53.1) | <0.001 |
| (n = 243) | PR | 18 (45.0) | 6 (10.0) | 6 (4.2) | 4 (7.7) | 26 (13.6) | 16 (8.2) | 14 (29.2) | |||
| SD | 6 (15.02) | 2 (3.3) | 5 (3.5) | 1 (1.9) | 12 (6.3) | 5 (2.6) | 1 (2.1) | ||||
| PD | 0 (0.0) | 1 (1.7) | 0 (0.0) | 0 (0.0) | 1 (0.5) | 0 (0.0) | 1 (2.1) | ||||
| TVT | CR | 9 (31.0) | 15 (75.0) | 6 (60.0) | 0.021 | 3 (42.9) | 27 (51.9) | 0.877 | 15 (60.0) | 15 (44.1) | 0.610 |
| (n = 59) | PR | 12 (41.4) | 3 (15.0) | 3 (30.0) | 3 (42.9) | 15 (28.9) | 7 (28.0) | 11 (32.4) | |||
| SD | 8 (27.6) | 1 (5.0) | 1 (10.0) | 1 (14.2) | 9 (17.3) | 3 (12.0) | 7 (20.6) | ||||
| PD | 0 (0.0) | 1 (5.0) | 0 (0.0) | 0 (0.0) | 1 (1.9) | 0 (0.0) | 1 (2.9) | ||||
Abbreviations: CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease; the others are the same as Table 1. * Fisher’s exact test.