Table 1.

Preclinical studies of tankyrase inhibitors with in vivo murine cancer models.

Disease Models	Cells	Drugs	References
Colorectal cancer xenograft model	COLO-320DM SW430	RK-287107	[16]
Colorectal cancer xenograft model	COLO-320DM HCT-15	G007-LK	[34]
Osteosarcoma xenograft model	MNNG-HOS	IWR-1	[24]
Gastrointestinal stromal tumor model(KitV558Δ/+ mouse model)	Gastrointestinal stromal tumor	G007-LK	[35]
Orthotopic lung cancer model	HCC4006 H1650 PC9T790M	AZ1366	[36]
Colorectal cancer xenograft model	Colorectal cancer	AZ1366	[37]
Colorectal cancer xenograft model	Colorectal cancer	NVP-TNKS656	[38]
Colorectal cancer xenograft model	COLO-320DM	G007-LK	[39]