Table 3.

Clinical studies involving MCL-1 inhibitors.

Clinical Trial. Gov Identifier	Clinical Trial	Molecular Target	Phase and Patients
NCT 02979366	Phase I study of S64315 administered intravenously in patients with acute myeloid leukemia and myelodysplastic syndrome	MCL-1 (BH3-groove)	I, relapsed/refractory AMLs or secondary MDSs
NCT o2675452	AMG 176 first in human trial in subjects with relapsed or refractory multiple myeloma and subjects with relapsed or refractory AML	MCL-1 (BH3-groove)	I, relapsed/refractory multiple myeloma and AML
NCT 03218683	Study of AZD 5991 in relapsed or refractory hematologic malignancies	MCL-1	I, relapsed/refractory hematologic malignancies