Figure 1.

The influence of VAS2870 (10 µM) on calcium signaling in response to histamine (10 μM) and agonist of PAR1 SFLLRN (2 µg/mL). (a) The curves represent the data of one of three experiments with similar results; (b) The bars represent the mean values of [Ca²⁺]_i increase in three independent experiments. [Ca²⁺]_i was measured as a relative increase in CalciumGreen fluorescence. In control experiments, the vehicle, dimethylsulfoxide (DMSO) at a final concentration 0.1%, was added instead of VAS2870.