Skip to main content
. 2019 Feb 5;11(2):180. doi: 10.3390/cancers11020180

Figure 3.

Figure 3

Rheological and elastic properties of 0.3% COL and 0.2% COL-0.5% AG gels and the effect of stromal cell elasticity on sample contraction. (a) Macroscopic images of both hydrogel cultures showing contraction of 0.3% COL only in the presence of MSC (inserts show histological HE stainings; * indicate the formation of elastic matrix; scale bars represent 200 µm). Rheological measurement of (b) 0.3% COL and (c) 0.2% COL-0.5% AG with a 5-step oscillatory test. A rapid increase in storage and loss moduli of 0.3% COL at low frequency (0.5 Hz) can be observed, in contrast to 0.2% COL-0.5% AG, which remained constant. G′ represents the storage modulus (squares) and G″ represents the loss modulus (circles).