Table 2.
Cumulative incidence of local recurrences (LR) and lymph node recurrences (LNR) and Kaplan-Meier estimates of distant recurrence-free survival (DRFS) and overall survival (OS) for patients of the different cohorts. BCS + RT: breast-conserving surgery with postoperative radiotherapy; Mastectomy: mastectomy without radiotherapy; y: years.
| Outcome | Treatment Modality | Entire Cohort | Case Control Cohort | ||||
|---|---|---|---|---|---|---|---|
| Diagnosis 1998–2014 | Diagnosis 1998–2014 | ||||||
| 7565 Patients | 1802 Patients | ||||||
| 5 y (%) |
10 y (%) |
p | 5 y (%) |
10 y (%) |
p | ||
| LR | <0.001 | 0.025 | |||||
| BCS + RT | 3.2 | 8.2 | 4.6 | 9.4 | |||
| Mastectomy | 5.0 | 12.6 | 4.8 | 12.9 | |||
| LNR | <0.001 | <0.001 | |||||
| BCS + RT | 0.9 | 2.2 | 0.7 | 2.0 | |||
| Mastectomy | 2.6 | 5.7 | 2.5 | 5.8 | |||
| DRFS | <0.001 | 0.013 | |||||
| BCS + RT | 94.5 | 90.2 | 93.8 | 89.4 | |||
| Mastectomy | 92.0 | 84.8 | 93.1 | 85.5 | |||
| OS | <0.001 | <0.001 | |||||
| BCS + RT | 95.2 | 86.7 | 93.8 | 85.3 | |||
| Mastectomy | 90.5 | 77.6 | 92.2 | 79.3 | |||