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. 2019 Feb 21;8(2):189. doi: 10.3390/cells8020189

Figure 1.

Figure 1

Comparison of the effect of NVP-BGJ398 and LY2874455 on proliferation and apoptosis of NRH-LS1 cells. (A) Proliferation of NRH-LS1 cells after inhibition of FGFR with either NVP-BGJ398 or LY2874455; one representative experiment is shown (n = 3), error bars represent the standard error of the mean (SEM) of technical replicates; (B) The number of cells with active caspase 3/7 during 96 h of treatment with either 100 nM of NVP-BGJ398 or 100 nM LY2874455, one representative experiment is shown (n = 3); (C) The percentage of apoptotic cells after 96 h of treatment with NVP-BGJ398 or LY2874455; the mean of experiments is shown (n = 3), error bars represent the standard deviation (SD) of the experiments. Representative images show apoptotic cells outlined in purple based on measured apoptotic signal. For all experiments untreated is with DMSO concentration corresponding to that of the highest drug concentration.