Table 1.
Demographics and clinical data of male patients with Parkinson disease and of controls.
| Participants Characteristics | Controls N = 35 |
PD N = 35 |
p-Value | Akinetic-Rigid PD N = 19 |
Mixed PD N = 16 |
p-Value |
|---|---|---|---|---|---|---|
| Median (IQR) | Median (IQR) | Median (IQR) | Median (IQR) | |||
| Age [years] | 55 (50;66) | 59 (54; 66) | 0.14 | 60 (54; 67) | 59 (55; 66) | 0.64 |
| Age at diagnosis [years] | 54 (49; 60) | 52 (47; 60) | 55 (53; 59) | 0.37 | ||
| PD duration [years] | 4.7 (2.5; 7.7) | 6.0 (3.6; 8.8) | 3.5 (1.5; 5.4) | 0.03 | ||
| MDS-UPDRS3 total score; range (0–132) |
1 (0; 2) | 34 (24; 43) | <0.0001 | 34 (24; 43) | 34.5 (25.5; 45.5) | 0.95 |
| MDS-UPDRS3 rigidity subscore; range (0–20) |
0 (0; 0) | 7 (3; 8) | <0.0001 | 7 (5; 8) | 4 (2.5; 8) | 0.10 |
| Tapping hits (left or more affected hand) |
186 (180; 205) | 164 (134; 184) | 0.0001 | 163 (143; 178) | 176 (126; 190) | 0.80 |
| Tremor amplitude (mm) (left or more affected hand) |
0.9 (0.7; 1.1) | 1.1 (0.8; 1.3) | 0.019 | 1.1 (0.8; 1.2) | 1.2 (0.8; 1.9) | 0.26 |
| N (%) | N (%) | N (%) | N % | |||
| Education | ||||||
| Low | 8 (22.9) | 17 (48.6) | 0.08 | 12 (63.2) | 5 (31.3) | 0.06 |
| Medium | 8 (22.9) | 6 (17.1) | 4 (21.1) | 2 (12.5) | ||
| High | 19 (54.3) | 12 (34.3) | 3 (15.8) | 9 (56.3) | ||
| Clinically more affected side | ||||||
| Left | 12 (34.3) | 5 (26.3) | 7 (43.8) | 0.24 | ||
| Right | 14 (40.0) | 7 (36.8) | 7 (43.8 | |||
| No preference | 9 (25.7) | 7 (36.8) | 2 (12.5) |
Abbreviations: IQR: inter-quartile range (25th; 75th percentile), PD: Parkinson’s disease, MDS-UPDRS3: Movement Disorder Society-Sponsored Revision of the Unified Parkinson Disease Rating Scale part III, p-value obtained by Kruskal–Wallis test or χ2 test (significant effects marked in bold and marginal effects marked in italic).