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. 2019 Feb 12;8(2):237. doi: 10.3390/jcm8020237

Table 2.

Association of intracerebral aneurysm development risk factors with internal carotid tortuosity descriptors.

Tortuosity Descriptor Women
(n = 227)
Men
(n = 71)
p-Value
Relative Length ± SD 0.49 ± 0.19 0.48 ± 0.18 0.812
Sum of Angle Metrics ± SD 0.37 ± 0.21 0.31 ± 0.21 0.028
Product of Angle Distance ± SD 0.37 ± 0.20 0.30 ± 0.20 0.016
Triangular Index ± SD 0.30 ± 0.13 0.25 ± 0.10 0.006
Inflection Count Metric ± SD 0.27 ± 0.15 0.23 ± 0.13 0.046
Hypertension
(n = 142)
No hypertension
(n = 156)
Relative Length ± SD 0.49 ± 0.18 0.48 ± 0.19 0.900
Sum of Angle Metrics ± SD 0.37 ± 0.22 0.35 ± 0.20 0.327
Product of Angle Distance ± SD 0.36 ± 0.21 0.35 ± 0.19 0.543
Triangular Index ± SD 0.30 ± 0.14 0.28 ± 0.11 0.210
Inflection Count Metric ± SD 0.27 ± 0.16 0.25 ± 0.13 0.204
Diabetes Mellitus
(n = 32)
No diabetes Mellitus
(n = 266)
Relative Length ± SD 0.47 ± 0.16 0.49 ± 0.19 0.573
Sum of Angle Metrics ± SD 0.35 ± 0.21 0.36 ± 0.21 0.811
Product of Angle Distance ± SD 0.35 ± 0.21 0.35 ± 0.20 0.953
Triangular Index ± SD 0.30 ± 0.17 0.28 ± 0.12 0.372
Inflection Count Metric ± SD 0.25 ± 0.13 0.26 ± 0.15 0.690
Smoking
(n = 38)
No Smoking
(n = 260)
Relative Length ± SD 0.51 ± 0.18 0.48 ± 0.19 0.312
Sum of Angle Metrics ± SD 0.37 ± 0.21 0.36 ± 0.21 0.758
Product of Angle Distance ± SD 0.38 ± 0.21 0.35 ± 0.20 0.379
Triangular Index ± SD 0.27 ± 0.11 0.29 ± 0.13 0.324
Inflection Count Metric ± SD 0.26 ± 0.13 0.26 ± 0.15 0.989
Hypercholesterolemia
(n = 20)
No Hypercholesterolemia
(n = 278)
Relative Length ± SD 0.52 ± 0.17 0.48 ± 0.19 0.403
Sum of Angle Metrics ± SD 0.31 ± 0.20 0.36 ± 0.21 0.268
Product of Angle Distance ± SD 0.31 ± 0.20 0.36 ± 0.20 0.336
Triangular Index ± SD 0.26 ± 0.11 0.29 ± 0.13 0.295
Inflection Count Metric ± SD 0.23 ± 0.11 0.26 ± 0.15 0.360
History of Heart Attack
(n = 5)
No History of Heart Attack
(n = 293)
Relative Length ± SD 0.48 ± 0.14 0.48 ± 0.19 0.964
Sum of Angle Metrics ± SD 0.40 ± 0.32 0.36 ± 0.21 0.658
Product of Angle Distance ± SD 0.43 ± 0.37 0.35 ± 0.20 0.379
Triangular Index ± SD 0.26 ± 0.08 0.29 ± 0.13 0.653
Inflection Count Metric ± SD 0.21 ± 0.07 0.26 ± 0.14 0.447
History of Ischemic Stroke (n = 28) No History of Ischemic Stroke (n = 270)
Relative Length ± SD 0.48 ± 0.16 0.48 ± 0.19 0.883
Sum of Angle Metrics ± SD 0.36 ± 0.22 0.36 ± 0.21 0.999
Product of Angle Distance ± SD 0.33 ± 0.23 0.36 ± 0.20 0.545
Triangular Index ± SD 0.30 ± 0.19 0.29 ± 0.12 0.582
Inflection Count Metric ± SD 0.25 ± 0.14 0.26 ± 0.14 0.724
History of Subarachnoid Hemorrhage (n = 18) No history of Subarachnoid Hemorrhage (n = 280)
Relative Length ± SD 0.53 ± 0.18 0.48 ± 0.19 0.284
Sum of Angle Metrics ± SD 0.42 ± 0.22 0.35 ± 0.21 0.176
Product of Angle Distance ± SD 0.46 ± 0.22 0.35 ± 0.20 0.024
Triangular Index ± SD 0.30 ± 0.08 0.29 ± 0.13 0.733
Inflection Count Metric ± SD 0.25 ± 0.13 0.26 ± 0.15 0.828