Table 2.

The Modena Criteria (AIOM Guidelines 2018).

BC and OC Diagnosed in The Same Patient

OC, fallopian tube or primary peritoneal cancer (excluded mucinous and borderline) at any age.

Male Breast Cancer.

Triple negative BC diagnosed ≤60 years.

BC diagnosed ≤ 35 years.

At least 1 BC and at least 1 OC.

At least 2 first-degree blood relative with BC, at least one diagnosed ≤ 40 years or bilateral.

Healthy individuals with an estimated risk of carrying a BRCA mutation ≥ 40%, calculated with the BRCAPro risk calculator (Version CaGene6)

BC: Breast Cancer; OC: ovarian cancer.