Table 3.
Statistic results of diffusion metric (FA, ADC, AD and RD) between the MDD and control groups.
| Inter-group comparison |
MDD vs.CTL |
||||
|---|---|---|---|---|---|
| Cerebral regions | Tracts | FA | ADC | AD | RD |
| Anterior cingulate | gCC | ↘ | ↗ | ↘ | ↗ |
| Cingulum gyrus | Cingulum | ↘ | ↗ | NS | ↗ |
| Insula | ILF | ↘ | ↗ | ↘ | ↗ |
| Thalamus | PTR | ↘ | ↗ | ↘ | ↗ |
| Parahippocampal gyrus | PLIC | ↗ | ↘ | ↘ | ↘ |
| Posterior cingulate | sCC | ↗ | ↘ | ↘ | ↘ |
Up and down arrows indicate significant increased and decreased of the diffusion metric (FA, ADC, AD and RD) in MDD group compared to healthy control group obtained with two-sample t-test (p < 0.05). Only the arrows in bold front correspond to changes, which survived after FDR correction (p ≤ 0.05). The acronym NS means no significant difference was found. gCC and sCC: genu and splenium of the Corpus Callosum, ILF: Inferior Longitudinal Fasciculus, PTR: Posterior Thalamic Radiation, PLIC: Posterior Limb of the Internal Capsule.