Table 1.
Summary of the National Lung Screening Trial (NLST) and the NELSON trials.
| NLST | NELSON | ||||
|---|---|---|---|---|---|
| Country | USA | BE/NL | |||
| Enrollment | 2002–2004 | 2003–NR | |||
| Number of Centers | 33 | 4 | |||
| Number of screens | 3 | ||||
| Screening planned at years | 1, 2 and 3 | 1, 2 and 4 | |||
| Comparison | LDCT vs. Xray | LDCT vs. usual care | |||
| Population | |||||
| Age | 55–74 | 50–69 (50–75) | |||
| Smoking (pack-years) | ≥30 | >15 * | |||
| Sex | both (male 59%) | men º (male 84%) | |||
| Years since quit | ≤15 | ≤10 | |||
| Patients Screened, n | 26,722 vs. 26,732 | 7907 vs. 7915 | |||
| Planned follow-up, y | >7 | 10 | |||
| Nodule Size warranting Follow-up | 2011 |  |
2009 |  |
+ VDT |
| 2014 | ≥100 mm3 (≥5 mm) |
+ VDT | |||
| LC diagnosed at screening, % | 1.02 | 0.9 | |||
| 5 mm Reduction of LC mortality | 20% | 26% a | |||
*, ≥15 cigarettes/day for 25 years or ≥10 cigarettes/day for 30 years; º, both in Belgium; VDT, volume doubling time; a, in men.