Table 2.

Inclusion criteria (study groups).

NeurOptimal (Trained Bruxistic Patients)		NeurOptimal (Trained Controls)
+ AE		+ AE
Inclusion Criteria	Inclusion Criteria	Inclusion Criteria	Inclusion Criteria
Bruxistic patients (n = 12, 120 saliva)	Bruxistic patients (n = 12, 120 saliva)	Control Subjects (n = 5, 15 saliva)	Control Subjects (n = 5, 15 saliva)
With stress DASS-42 > 16–25 (Stress item)	With stress DASS-42 > 16–25 (Stress item)	Without stress DASS-42 (0–14) (for the Stress item)	Without stress DASS-42 (0–14) (for the Stress item)
Bruxism test and underwent oral examination (a good healthy state)	Bruxism test and underwent oral examination (a good healthy state)	Without Bruxism (oral examination and a good healthy state)	Without Bruxism
Trained in NeurOptimal (NO): 21 sessions	Trained in NO (21 sessions)	Trained in NO (12 sessions)	Trained in NO (12 sessions)
Exposed to Origanum majorana essential oil during 21 sessions	They underwent 21 NO sessions without Origanum majorana essential oil	Exposed to Origanum majorana essential oil during 12 sessions	Exposed to placebo (neutral oil) in 12 NO
Inclusion Criteria	Inclusion Criteria	Exclusion Criteria (for all groups)	Inclusion Criteria
Bruxistic patients (n = 30, 120 salive)	Control Subjects (n = 5, 50 saliva)	Periodontal disease or gingivitis	Control Subjects (n = 30, 60 saliva)
With stress: DASS-42 > 16–25 (Stress item)	Without stress DASS-42 (0–14) (for the Stress item)	presence of bacterial plaque	Without stress: DASS-42 (0–14) (for the Stress item)
Bruxism test and underwent oral examination (a good healthy state)	Without Bruxism (oral examination and a good healthy state).	Orthodontic devices	Without Bruxism
Without NeurOptimal (NO) training	Without Origanum majorana essential oil exposure	the use of removable partial denture	Without NO training
			Unexposed to Origanum majorana

+ AE: patients who smell Origanum majorana essential oil.