Figure 1.

Glioblastoma stem cells (GSCs) exhibit robust radioresistance. (A) Viability as determined by trypan blue exclusion assay of Glio9 (white), Glio11 (blue), and Glio14 (red) treated with increasing doses of radiation and then analyzed 72 h after exposure. Results are representative of at least three experiments and displayed as mean ± SEM. (B) Light microscopy images of GSC neurosphere phenotype with and without radiation treatment. Magnification: 10×. (C) Western blot of p-H2AX, a marker for double strand breaks, in GSCs exposed to increasing radiation.