Figure 3.

Soluble CD200 (sCD200) predicts tumor recurrence prior to MRI evidence. (A) Serum levels of sCD200 decreased after surgery and vaccinations of autologous tumor lysate + CD200AR-L in one Boston terrier with a grade III glioma. (B) Serum sCD200 increased at 1 year although there was no evidence of tumor recurrence on the MRI at that time. (C) Six months later, an MRI was repeated when the dog developed severe breakthrough generalized seizure activity and tumor progression was seen (red circle).